Pharmacokinetics of various forms of application
| Oral | Sublingual | Inhalative | |
|---|---|---|---|
| cannabis extract, monosubstances (dronabinol, nabilone) | cannabis extract | cannabis flowers | |
| onset of action | 30-90 min | 15-45 mins | seconds to minutes after ingestion |
| Peak plasma concentration | 1-6 hours | 30-90 min | 15-30 mins |
| To note | First-pass metabolism in liver Conversion of THC to active metabolite 11-OH-THC increases effect | No first-pass effect in the liver | With MIGHTY MEDIC® (handheld) or VOLCANO DIGIT® (desktop) vaporizers No first-pass effect in the liver |
Factors for choosing the appropriate form of application | Long-lasting effect Suitable for evening use Easy, discreet intake | No first-pass metabolism in the liver High bioavailability Easy dose finding Discreet application suitable for beginners | Long-lasting effect Suitable for evening use Easy, discreet intake |